A National Land Information System (NLIS) is a geographic information system for cadastral and land-use mapping, typically used by local government. Similar to a GIS, an NLIS is designed specifically to contain spatially references land related data for a defined area and procedures and techniques for the systematic collection, update, processing and distribution of this data. A NLIS is a decision-making tool that creates, visualizes, analyzes, reports and publishes land-based data such as parcel information, zoning, land use, ownership and general property information. In addition to those land related data, the NLIS may contain other additional information such as data on soils, hydrology, rainfall or socio-economic information. The increasing pressures for land in developing and emerging countries in addition to tenure systems eroded or sometimes abandoned, the need for a formal system becomes real. Therefore, many countries have recognized the land information systems as a powerful and an undisputable tool. The implementation of land information system leads to a decreasing number of land related disputes, reduces the risks of fraud or bribes, secure land for both local administrations and beneficiaries and encourages investments. NLIS is a performing tool that contributes to reduce poverty. The NLIS that will be established in Uganda under the DeSINLISI Project will be configured to support first, subsequent and miscellaneous registration in the Ministry of Lands Housing and Urban Development (MLHUD). The NLIS will replace the current manual system of land allocation, deed plan preparation and land registration.